NIOSH Centers of Excellence for Total Worker Health® (U19)

id: 363369
Source ↗ · id

opportunityNumber: RFA-OH-27-049
Source ↗ · opportunityNumber

opportunityTitle: NIOSH Centers of Excellence for Total Worker Health® (U19)
Source ↗ · opportunityTitle

revision: 0
Source ↗ · revision

agencyDetails: {"code":"HHSCDCERA","seed":"HHS-CDC-HHSCDCERA","agencyName":"Centers for Disease Control and Prevention - ERA","agencyCode":"HHS-CDC-HHSCDCERA","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-CDC-HHSCDCERA
Source ↗ · owningAgencyCode

cfdas: [{"id":434782,"opportunityId":363369,"cfdaNumber":"93.262","programTitle":"Occupational Safety and Health Program"}]
Source ↗ · cfdas

forecastDesc: <p><strong>PURPOSE</strong><br>NIOSH intends to support the Centers of Excellence in Total Worker Health® (TWH).&nbsp;These Centers will conduct rigorous research and translation activities to prevent harmful exposures, improve working conditions, and advance worker well-being. The Centers will develop practical, scalable solutions for employers and workers. All projects must use the NIOSH Worker Well-Being Questionnaire (WellBQ) and share data with the HERO Worker Well-Being Clearinghouse. Large Research Projects&nbsp;require&nbsp;economic evaluation.&nbsp;</p><p><strong>PRIORITY AREAS</strong><br>• High-risk occupations: First responders, vehicle mechanics, and technicians, with emphasis on occupational exposures, related health risks, and prevention strategies<br>• Young workers, SMEs&nbsp;<br>• Chronic disease<br>• Mental health, stress<br>• Substance use disorder<br>• Artificial intelligence (AI), digital technologies</p><p>This is a multi-component NOFO.</p><p><strong>COMPONENT STRUCTURE</strong><br>Percentages indicate maximum share of total budget.</p><p><strong>Overall Component (Required)</strong><br>Provides Center leadership and integration. Applicants should show strong coordination, scientific direction, and alignment across projects.</p><p><strong>Administration, Evaluation, and Emerging Issues Core (Required; up to 15%)</strong><br>Supports management and Center-wide evaluation. Applicants should describe oversight, data governance, and quality assurance.Optional activities include emerging issues and shared research resources.</p><p><strong>Outreach, Dissemination, and Impact Core (Required; up to 15%)</strong><br>Supports communication, worker/employer engagement, training, translation, implementation, and dissemination strategies.</p><p><strong>Research Projects (Required; about 60 to 70%)</strong><br>Includes all research activities. Applicants may propose&nbsp;a mix of&nbsp;projects.&nbsp;Research project distinctions are based on scope and complexity rather than cost. Projects should demonstrate scientific rigor and potential for sustained impact.</p><ul><li data-list-item-id="ea042ead4bda90f7afca9db4ed6265ccb"><i><strong>Small Research Projects (Required; at least one project; up to 3 years)</strong></i><br>Exploratory, feasibility, early-stage intervention, surveillance, or measurement studies.<br>Priority areas: high-risk occupations, young workers, SMEs.<br>Should show innovation and potential to expand.&nbsp;</li><li data-list-item-id="eab66fe3983b477c58a224d9b02cf204c"><i><strong>Large Research Projects (Required; at least one project; up to 5 years)</strong></i><br>Multiyear etiologic, mechanistic, intervention, or translational studies.<br>Priority areas: chronic disease, mental health, substance use disorder.&nbsp;<br>Economic evaluation&nbsp;is required. Projects should include strong design and analytic plans.&nbsp;</li><li data-list-item-id="ed259d50833d70d74aa5cc6f2b4cd83d6"><i><strong>Pilot/Feasibility Program (Optional; 12–18 months)</strong></i>&nbsp;<br>Short-term studies generating preliminary data or testing AI/digital technology approaches.</li></ul>
Source ↗ · forecastDesc

applicantTypes: [{"id":"22","description":"For profit organizations other than small businesses"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"00","description":"State governments"},{"id":"05","description":"Independent school districts"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"23","description":"Small businesses"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"20","description":"Private institutions of higher education"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"99","description":"Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled \"Additional Information on Eligibility\""},{"id":"01","description":"County governments"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"04","description":"Special district governments"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"CA","description":"Cooperative Agreement"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

awardFloor: 500000
Source ↗ · awardFloor

awardCeiling: 1400000
Source ↗ · awardCeiling

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Jul 28, 2026 07:10:40 PM EDT
Source ↗ · lastUpdatedDate

status: forecasted
Source ↗ · oppHits[id=363369].oppStatus