forecasted
Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center
National Institutes of Health · PAR-27-136
See source for award amount
Not specified
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Independent school districts, County governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), State governments, Private institutions of higher education, City or township governments, Native American tribal organizations (other than Federally recognized tribal governments), Public housing authorities/Indian housing authorities, Special district governments, Small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification)
Geographic eligibility and all attachment-specific conditions require review of the original announcement.
Eligibility details
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Matching funds & resources
Source matching-funds field: Not Required.
Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.
About this opportunity
NINDS intends to support a Diagnostic Research Innovation Center (DRIC) for the next phase of the Undiagnosed Diseases Network (UDN). The new Network is expected to include a Clinical and Data Coordinating Center (CDCC), geographically distributed clinical Networks of Diagnostic Excellence (NODEs), the NIH Undiagnosed Diseases Program (UDP), a DRIC, the UDN Foundation, patient advocacy organizations, NIH, and other stakeholders. The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases of the UDN. The DRIC is expected to test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working closely with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human in vitro models, and the development of non-genetic diagnostic strategies. Collaborating with the Network, the DRIC will contribute to the discovery of novel disease-associated genes and genomic variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes. Support is expected for an integrated center that brings together complementary capabilities and investigators with demonstrated scientific synergy and prior collaboration. Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, and develop responsive projects.
Funding geography: Not specified — review source. A funder’s address does not establish eligibility.
Review original source ↗Funding instrument: Cooperative Agreement. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.
Source fields and evidence
id: 363837
Source ↗ · id
opportunityNumber: PAR-27-136
Source ↗ · opportunityNumber
opportunityTitle: Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center
Source ↗ · opportunityTitle
revision: 0
Source ↗ · revision
agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails
owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode
cfdas: [{"id":435372,"opportunityId":363837,"cfdaNumber":"93.853","programTitle":"Extramural Research Programs in the Neurosciences and Neurological Disorders"}]
Source ↗ · cfdas
forecastDesc: <p>NINDS intends to support a Diagnostic Research Innovation Center (DRIC) for the next phase of the Undiagnosed Diseases Network (UDN). The new Network is expected to include a Clinical and Data Coordinating Center (CDCC), geographically distributed clinical Networks of Diagnostic Excellence (NODEs), the NIH Undiagnosed Diseases Program (UDP), a DRIC, the UDN Foundation, patient advocacy organizations, NIH, and other stakeholders. The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases of the UDN.</p><p>The DRIC is expected to test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working closely with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human <i>in vitro</i> models, and the development of non-genetic diagnostic strategies. Collaborating with the Network, the DRIC will contribute to the discovery of novel disease-associated genes and genomic variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes. Support is expected for an integrated center that brings together complementary capabilities and investigators with demonstrated scientific synergy and prior collaboration. </p><p>Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, and develop responsive projects.</p>
Source ↗ · forecastDesc
applicantTypes: [{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"05","description":"Independent school districts"},{"id":"01","description":"County governments"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"00","description":"State governments"},{"id":"20","description":"Private institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"04","description":"Special district governments"},{"id":"23","description":"Small businesses"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"}]
Source ↗ · applicantTypes
applicantEligibilityDesc: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Source ↗ · applicantEligibilityDesc
fundingInstruments: [{"id":"CA","description":"Cooperative Agreement"}]
Source ↗ · fundingInstruments
fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories
costSharing: false
Source ↗ · costSharing
lastUpdatedDate: Sep 10, 2026 08:51:20 AM EDT
Source ↗ · lastUpdatedDate
status: forecasted
Source ↗ · oppHits[id=363837].oppStatus
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