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forecasted

Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

National Institutes of Health · PAR-27-039

Award range

See source for award amount

Deadline

Not specified

Eligible applicants

Small businesses

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Eligibility details

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

The National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC), including the participating Institutes, Centers and Offices, intend to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, and Fast-Track (NIH only) grant applications for the Small Business Transition Grant. Through this NOFO, NIH and CDC will support early-career scientists as they transition into entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R43/R44 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH and CDC awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project.

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 362576
Source ↗ · id

opportunityNumber: PAR-27-039
Source ↗ · opportunityNumber

opportunityTitle: Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)
Source ↗ · opportunityTitle

revision: 0
Source ↗ · revision

agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode

cfdas: [{"id":433617,"opportunityId":362576,"cfdaNumber":"93.113","programTitle":"Environmental Health"},{"id":433628,"opportunityId":362576,"cfdaNumber":"93.121","programTitle":"Oral Diseases and Disorders Research"},{"id":433632,"opportunityId":362576,"cfdaNumber":"93.143","programTitle":"NIEHS Superfund Hazardous Substances_Basic Research and Education"},{"id":433635,"opportunityId":362576,"cfdaNumber":"93.172","programTitle":"Human Genome Research"},{"id":433626,"opportunityId":362576,"cfdaNumber":"93.173","programTitle":"Research Related to Deafness and Communication Disorders"},{"id":433619,"opportunityId":362576,"cfdaNumber":"93.213","programTitle":"Research and Training in Complementary and Integrative Health"},{"id":433620,"opportunityId":362576,"cfdaNumber":"93.233","programTitle":"National Center on Sleep Disorders Research"},{"id":433627,"opportunityId":362576,"cfdaNumber":"93.273","programTitle":"Alcohol Research Programs"},{"id":433622,"opportunityId":362576,"cfdaNumber":"93.279","programTitle":"Drug Use and Addiction Research Programs"},{"id":433637,"opportunityId":362576,"cfdaNumber":"93.350","programTitle":"National Center for Advancing Translational Sciences"},{"id":433638,"opportunityId":362576,"cfdaNumber":"93.361","programTitle":"Nursing Research"},{"id":433624,"opportunityId":362576,"cfdaNumber":"93.837","programTitle":"Cardiovascular Diseases Research"},{"id":433629,"opportunityId":362576,"cfdaNumber":"93.838","programTitle":"Lung Diseases Research"},{"id":433618,"opportunityId":362576,"cfdaNumber":"93.839","programTitle":"Blood Diseases and Resources Research"},{"id":433623,"opportunityId":362576,"cfdaNumber":"93.840","programTitle":"Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders"},{"id":433631,"opportunityId":362576,"cfdaNumber":"93.846","programTitle":"Arthritis, Musculoskeletal and Skin Diseases Research"},{"id":433633,"opportunityId":362576,"cfdaNumber":"93.847","programTitle":"Diabetes, Digestive, and Kidney Diseases Extramural Research"},{"id":433636,"opportunityId":362576,"cfdaNumber":"93.859","programTitle":"Biomedical Research and Research Training"},{"id":433621,"opportunityId":362576,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research"},{"id":433634,"opportunityId":362576,"cfdaNumber":"93.866","programTitle":"Aging Research"},{"id":433630,"opportunityId":362576,"cfdaNumber":"93.867","programTitle":"Vision Research"},{"id":433625,"opportunityId":362576,"cfdaNumber":"93.879","programTitle":"Medical Library Assistance"}]
Source ↗ · cfdas

forecastDesc: <p>The National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC), including the participating Institutes, Centers and Offices, intend to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, and Fast-Track (NIH only) grant applications for the Small Business Transition Grant. Through this NOFO, NIH and CDC will support early-career scientists as they transition into entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI.</p><p>Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R43/R44 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&amp;D mission(s) of the NIH and CDC awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project.&nbsp;</p>
Source ↗ · forecastDesc

applicantTypes: [{"id":"23","description":"Small businesses"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: May 27, 2026 02:02:35 PM EDT
Source ↗ · lastUpdatedDate

status: forecasted
Source ↗ · oppHits[id=362576].oppStatus

Source retrieved 10/16/2026 · Revision 0. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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