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forecasted

HIV/AIDS Clinical Trials Network Leadership and Operations Centers

National Institutes of Health · RFA-AI-28-001

Award range

See source for award amount

Deadline

Not specified

Eligible applicants

Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Special district governments, Native American tribal organizations (other than Federally recognized tribal governments), Small businesses, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, County governments, For profit organizations other than small businesses, Independent school districts, Native American tribal governments (Federally recognized), City or township governments, Public housing authorities/Indian housing authorities, Others (see text field entitled "Additional Information on Eligibility" for clarification)

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Eligibility details

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting four Clinical Trials Networks (CTNs) each comprised of a Leadership and Operations Center (LOC), Statistical and Data Management Center, and Laboratory Center working with Clinical Trials Units to advance prevention, treatment, and implementation research designed to end the HIV epidemic. This NOFO will solicit applications for four LOCs to provide scientific leadership, research prioritization, and conduct studies in a CTN. A LOC develops the research agenda in one of these areas: 1) HIV therapeutics/cure, and prevention/treatment for HIV-associated comorbidities in adults; 2) HIV prevention/treatment in maternal/adolescent/pediatric populations; 3) biomedical HIV prevention strategies for adults/adolescents; and 4) immune-based prevention for HIV and HIV-associated diseases. CTNs will conduct HIV implementation research improving uptake of evidence-based prevention and treatment strategies across the lifespan. High impact LOC studies will produce crucial findings significantly benefiting Americans with or at-risk of HIV and HIV-associated diseases. Grant authorities that allow NIAID to forecast this opportunity are: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Cooperative Agreement. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 361815
Source ↗ · id

opportunityNumber: RFA-AI-28-001
Source ↗ · opportunityNumber

opportunityTitle: HIV/AIDS Clinical Trials Network Leadership and Operations Centers
Source ↗ · opportunityTitle

revision: 0
Source ↗ · revision

agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode

cfdas: [{"id":432597,"opportunityId":361815,"cfdaNumber":"93.310","programTitle":"Trans-NIH Research Support"},{"id":432598,"opportunityId":361815,"cfdaNumber":"93.855","programTitle":"Allergy and Infectious Diseases Research"}]
Source ↗ · cfdas

forecastDesc: <p>The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting four Clinical Trials Networks (CTNs) each comprised of a Leadership and Operations Center (LOC), Statistical and Data Management Center, and Laboratory Center working with Clinical Trials Units to advance prevention,&nbsp;treatment, and implementation&nbsp;research&nbsp;designed to end the HIV epidemic. This NOFO will solicit applications for four LOCs to provide scientific leadership, research prioritization, and conduct studies in a CTN.&nbsp;A LOC develops the research agenda in one of these areas: 1) HIV therapeutics/cure, and prevention/treatment for HIV-associated comorbidities in adults; 2) HIV prevention/treatment in maternal/adolescent/pediatric populations; 3) biomedical HIV prevention strategies for adults/adolescents; and 4) immune-based prevention for HIV and HIV-associated diseases. CTNs will conduct HIV implementation research improving uptake of evidence-based prevention and treatment strategies across the lifespan. High impact LOC studies will produce crucial findings significantly benefiting Americans with or at-risk of HIV and HIV-associated diseases.</p><p>Grant authorities that allow NIAID to forecast this opportunity are: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.</p>
Source ↗ · forecastDesc

applicantTypes: [{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"04","description":"Special district governments"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"23","description":"Small businesses"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"00","description":"State governments"},{"id":"01","description":"County governments"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"05","description":"Independent school districts"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"02","description":"City or township governments"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"CA","description":"Cooperative Agreement"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Apr 08, 2026 03:23:53 PM EDT
Source ↗ · lastUpdatedDate

status: forecasted
Source ↗ · oppHits[id=361815].oppStatus

Source retrieved 10/15/2026 · Revision 0. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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