NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)

id: 359758
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opportunityNumber: PA-27-101
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opportunityTitle: NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)
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revision: 6
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agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
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owningAgencyCode: HHS-NIH11
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cfdas: [{"id":429878,"opportunityId":359758,"cfdaNumber":"93.233","programTitle":"National Center on Sleep Disorders Research"},{"id":429882,"opportunityId":359758,"cfdaNumber":"93.242","programTitle":"Mental Health Research Grants"},{"id":429870,"opportunityId":359758,"cfdaNumber":"93.273","programTitle":"Alcohol Research Programs"},{"id":429887,"opportunityId":359758,"cfdaNumber":"93.307","programTitle":"Minority Health and Health Disparities Research"},{"id":432681,"opportunityId":359758,"cfdaNumber":"93.313","programTitle":"NIH Office of Research on Women's Health"},{"id":432680,"opportunityId":359758,"cfdaNumber":"93.350","programTitle":"National Center for Advancing Translational Sciences"},{"id":432679,"opportunityId":359758,"cfdaNumber":"93.351","programTitle":"Research Infrastructure Programs"},{"id":429879,"opportunityId":359758,"cfdaNumber":"93.393","programTitle":"Cancer Cause and Prevention Research"},{"id":429875,"opportunityId":359758,"cfdaNumber":"93.394","programTitle":"Cancer Detection and Diagnosis Research"},{"id":429885,"opportunityId":359758,"cfdaNumber":"93.395","programTitle":"Cancer Treatment Research"},{"id":429863,"opportunityId":359758,"cfdaNumber":"93.837","programTitle":"Cardiovascular Diseases Research"},{"id":429884,"opportunityId":359758,"cfdaNumber":"93.838","programTitle":"Lung Diseases Research"},{"id":429877,"opportunityId":359758,"cfdaNumber":"93.839","programTitle":"Blood Diseases and Resources Research"},{"id":429873,"opportunityId":359758,"cfdaNumber":"93.840","programTitle":"Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders"},{"id":429881,"opportunityId":359758,"cfdaNumber":"93.847","programTitle":"Diabetes, Digestive, and Kidney Diseases Extramural Research"},{"id":432683,"opportunityId":359758,"cfdaNumber":"93.853","programTitle":"Extramural Research Programs in the Neurosciences and Neurological Disorders"},{"id":432682,"opportunityId":359758,"cfdaNumber":"93.855","programTitle":"Allergy and Infectious Diseases Research"},{"id":432684,"opportunityId":359758,"cfdaNumber":"93.859","programTitle":"Biomedical Research and Research Training"},{"id":429872,"opportunityId":359758,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research"},{"id":429865,"opportunityId":359758,"cfdaNumber":"93.866","programTitle":"Aging Research"},{"id":429883,"opportunityId":359758,"cfdaNumber":"93.867","programTitle":"Vision Research"},{"id":433703,"opportunityId":359758}]
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applicantTypes: [{"id":"23","description":"Small businesses"}]
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applicantEligibilityDesc: Only United States small business concerns (SBCs) that have previously received an NIH SBIR or STTR Phase II award are eligible to submit applications for this opportunity. Only one NIH Phase IIB Strategic Breakthrough award is allowed per project. This NOFO supports Renewal/Resubmission "Type 2" Applications from recipients with NIH Phase II SBIR/STTR awards that are submitted within the first six due dates following the expiration of their budget period. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
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fundingInstruments: [{"id":"G","description":"Grant"}]
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fundingActivityCategories: [{"id":"HL","description":"Health"}]
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awardFloor: none
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awardCeiling: none
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responseDate: Apr 05, 2029 12:00:00 AM EDT
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responseDateStr: 2029-04-05-00-00-00
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costSharing: true
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lastUpdatedDate: Jun 01, 2026 12:56:46 PM EDT
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status: posted
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