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Posted opportunity — confirm at source

BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)

National Institutes of Health · RFA-NS-24-031

Award range

Up to $750,000

Deadline

2027-01-28-00-00-00

Confirm exact timezone in the announcement.
Eligible applicants

Small businesses, For profit organizations other than small businesses, County governments, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Private institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification), State governments, Independent school districts, City or township governments, Special district governments, Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments)

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Eligibility details

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or diagnose central nervous system (CNS) diseases and disorders and to better understand the human CNS, from proof of concept up to the stage of readiness for first in human (FIH) studies. Technologies may incorporate any signal modality (e.g., electrical, optical, magnetic, acoustic) or a combination thereof. Diverse team-based applications that integrate appropriate domains of expertise are encouraged.

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 353055
Source ↗ · id

opportunityNumber: RFA-NS-24-031
Source ↗ · opportunityNumber

opportunityTitle: BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)
Source ↗ · opportunityTitle

revision: 1
Source ↗ · revision

agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode

cfdas: [{"id":418409,"opportunityId":353055,"cfdaNumber":"93.173","programTitle":"Research Related to Deafness and Communication Disorders"},{"id":418403,"opportunityId":353055,"cfdaNumber":"93.213","programTitle":"Research and Training in Complementary and Integrative Health"},{"id":418404,"opportunityId":353055,"cfdaNumber":"93.242","programTitle":"Mental Health Research Grants"},{"id":418405,"opportunityId":353055,"cfdaNumber":"93.273","programTitle":"Alcohol Research Programs"},{"id":418406,"opportunityId":353055,"cfdaNumber":"93.279","programTitle":"Drug Abuse and Addiction Research Programs"},{"id":418408,"opportunityId":353055,"cfdaNumber":"93.286","programTitle":"Discovery and Applied Research for Technological Innovations to Improve Human Health"},{"id":418401,"opportunityId":353055,"cfdaNumber":"93.853","programTitle":"Extramural Research Programs in the Neurosciences and Neurological Disorders"},{"id":418400,"opportunityId":353055,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research"},{"id":418402,"opportunityId":353055,"cfdaNumber":"93.866","programTitle":"Aging Research"},{"id":418407,"opportunityId":353055,"cfdaNumber":"93.867","programTitle":"Vision Research"},{"id":420100,"opportunityId":353055}]
Source ↗ · cfdas

applicantTypes: [{"id":"23","description":"Small businesses"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"01","description":"County governments"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"20","description":"Private institutions of higher education"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"00","description":"State governments"},{"id":"05","description":"Independent school districts"},{"id":"02","description":"City or township governments"},{"id":"04","description":"Special district governments"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"ED","description":"Education"},{"id":"HL","description":"Health"},{"id":"ISS","description":"Income Security and Social Services"}]
Source ↗ · fundingActivityCategories

awardFloor: none
Source ↗ · awardFloor

awardCeiling: 750000
Source ↗ · awardCeiling

responseDate: Jan 28, 2027 12:00:00 AM EST
Source ↗ · responseDate

responseDateStr: 2027-01-28-00-00-00
Source ↗ · responseDateStr

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Mar 19, 2024 12:32:41 PM EDT
Source ↗ · lastUpdatedDate

status: posted
Source ↗ · oppHits[id=353055].oppStatus

Source retrieved 10/15/2026 · Revision 1. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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