forecasted
Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis
National Institutes of Health · RFA-RM-28-006
Up to $500,000
Not specified
State governments, Special district governments, Small businesses, Public and State controlled institutions of higher education, City or township governments, For profit organizations other than small businesses, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Public housing authorities/Indian housing authorities, Private institutions of higher education, Independent school districts, Native American tribal governments (Federally recognized), Others (see text field entitled "Additional Information on Eligibility" for clarification), County governments, Native American tribal organizations (other than Federally recognized tribal governments)
Geographic eligibility and all attachment-specific conditions require review of the original announcement.
Eligibility details
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Matching funds & resources
Source matching-funds field: Not Required.
Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.
About this opportunity
The NIH Common Fund, in partnership with other NIH Institutes and Centers, plans to issue Notices of Funding Opportunity (NOFOs) for the RNomics program, which seeks to develop tools for studying the full set of RNA molecules (the RNome) in cells and tissues. The program will support technologies and resources that enable integrated analysis of RNA sequences, modifications, structures, locations, interactions, and functions to advance understanding of health and disease. RNomics includes four initiatives: technology enhancement centers, transformative technologies, molecular standards, and a coordinating center. Applications are not being solicited at this time. This notice is being provided to give potential applicants time to develop meaningful collaborations and strong projects. This NOFO will support the transformative technologies initiative. These phased projects will develop new experimental and computational RNA technologies that address major limitations of current methods. Projects will focus on early-stage, high-risk ideas not yet demonstrated at scale or in biologically relevant systems. Priority areas include tools to sequence RNA, detect modifications, study RNA function, and analyze RNA across molecules, cells, and tissues. Projects that successfully complete Phase 1 milestones will be evaluated for transition to Phase 2. Phase 2 projects are expected to deliver validated tools for community use.
Funding geography: Not specified — review source. A funder’s address does not establish eligibility.
Review original source ↗Funding instrument: Cooperative Agreement. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.
Source fields and evidence
id: 363474
Source ↗ · id
opportunityNumber: RFA-RM-28-006
Source ↗ · opportunityNumber
opportunityTitle: Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis
Source ↗ · opportunityTitle
revision: 0
Source ↗ · revision
agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails
owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode
cfdas: [{"id":434906,"opportunityId":363474,"cfdaNumber":"93.310","programTitle":"Trans-NIH Research Support"}]
Source ↗ · cfdas
forecastDesc: <p>The NIH Common Fund, in partnership with other NIH Institutes and Centers, plans to issue Notices of Funding Opportunity (NOFOs) for the RNomics program, which seeks to develop tools for studying the full set of RNA molecules (the RNome) in cells and tissues. The program will support technologies and resources that enable integrated analysis of RNA sequences, modifications, structures, locations, interactions, and functions to advance understanding of health and disease. RNomics includes four initiatives: technology enhancement centers, transformative technologies, molecular standards, and a coordinating center. Applications are not being solicited at this time. This notice is being provided to give potential applicants time to develop meaningful collaborations and strong projects. </p><p>This NOFO will support the transformative technologies initiative. These phased projects will develop new experimental and computational RNA technologies that address major limitations of current methods. Projects will focus on early-stage, high-risk ideas not yet demonstrated at scale or in biologically relevant systems. Priority areas include tools to sequence RNA, detect modifications, study RNA function, and analyze RNA across molecules, cells, and tissues. Projects that successfully complete Phase 1 milestones will be evaluated for transition to Phase 2. Phase 2 projects are expected to deliver validated tools for community use.</p>
Source ↗ · forecastDesc
applicantTypes: [{"id":"00","description":"State governments"},{"id":"04","description":"Special district governments"},{"id":"23","description":"Small businesses"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"20","description":"Private institutions of higher education"},{"id":"05","description":"Independent school districts"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"01","description":"County governments"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"}]
Source ↗ · applicantTypes
applicantEligibilityDesc: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Source ↗ · applicantEligibilityDesc
fundingInstruments: [{"id":"CA","description":"Cooperative Agreement"}]
Source ↗ · fundingInstruments
fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories
awardCeiling: 500000
Source ↗ · awardCeiling
costSharing: false
Source ↗ · costSharing
lastUpdatedDate: Aug 05, 2026 01:21:56 PM EDT
Source ↗ · lastUpdatedDate
status: forecasted
Source ↗ · oppHits[id=363474].oppStatus
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