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forecasted

Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases

National Institutes of Health · RFA-AI-28-014

Award range

See source for award amount

Deadline

Not specified

Eligible applicants

Private institutions of higher education, Small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Public housing authorities/Indian housing authorities, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), County governments, Independent school districts, Special district governments, For profit organizations other than small businesses, Public and State controlled institutions of higher education, City or township governments, State governments, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Eligibility details

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by supporting multidisciplinary, consortium-based research using precision systems biology approaches to uncover links among chronic illnesses, infectious diseases and microbiomes. There is an urgent scientific and clinical need to understand the pathways by which infections lead to chronic lifelong health issues or alternatively, how long-term illnesses might predispose or exacerbate acute infections. The objective is to harness cutting-edge technologies along with longitudinal patient cohorts and biobank data for comprehensive analysis of genetic, environmental, and lifestyle factors leading to advances in prevention and treatment strategies for both chronic and infectious diseases. The cutting-edge technologies may include multi-omics, computational modeling, artificial intelligence, organoid-based validation systems, and integration of real-world data, alongside improved access to digital health records and advanced clinical informatics tools. The goal is to generate meaningful insights into disease progression and host-pathogen interactions. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Cooperative Agreement. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 362952
Source ↗ · id

opportunityNumber: RFA-AI-28-014
Source ↗ · opportunityNumber

opportunityTitle: Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases
Source ↗ · opportunityTitle

revision: 0
Source ↗ · revision

agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode

cfdas: [{"id":434287,"opportunityId":362952,"cfdaNumber":"93.855","programTitle":"Allergy and Infectious Diseases Research"},{"id":434288,"opportunityId":362952,"cfdaNumber":"93.866","programTitle":"Aging Research"}]
Source ↗ · cfdas

forecastDesc: <p>The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by supporting multidisciplinary, consortium-based research using precision systems biology approaches to uncover links among chronic illnesses, infectious diseases and microbiomes. There is an urgent scientific and clinical need to understand the pathways by which infections lead to chronic lifelong health issues or alternatively, how long-term illnesses might predispose or exacerbate acute infections. The objective is to harness cutting-edge technologies along with longitudinal patient cohorts and biobank data for comprehensive analysis of genetic, environmental, and lifestyle factors leading to advances in prevention and treatment strategies for both chronic and infectious diseases. The cutting-edge technologies may include multi-omics, computational modeling, artificial intelligence, organoid-based validation systems, and integration of real-world data, alongside improved access to digital health records and advanced clinical informatics tools. The goal is to generate meaningful insights into disease progression and host-pathogen interactions. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.</p>
Source ↗ · forecastDesc

applicantTypes: [{"id":"20","description":"Private institutions of higher education"},{"id":"23","description":"Small businesses"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"01","description":"County governments"},{"id":"05","description":"Independent school districts"},{"id":"04","description":"Special district governments"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"00","description":"State governments"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"CA","description":"Cooperative Agreement"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Jun 24, 2026 01:51:14 PM EDT
Source ↗ · lastUpdatedDate

status: forecasted
Source ↗ · oppHits[id=362952].oppStatus

Source retrieved 10/15/2026 · Revision 0. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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