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forecasted

Notice of Intent to Publish a Funding Opportunity Announcement for Trailblazer Award for New and Early-Stage Investigators (R21 Clinical Trial Optional)

National Institutes of Health · FOR-EB-26-001

Award range

See source for award amount

Deadline

Not specified

Eligible applicants

State governments, Public housing authorities/Indian housing authorities, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Native American tribal organizations (other than Federally recognized tribal governments), Public and State controlled institutions of higher education, Independent school districts, Small businesses, Native American tribal governments (Federally recognized), Private institutions of higher education, County governments, For profit organizations other than small businesses

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

The National Institute of Biomedical Imaging and Bioengineering, with the National Eye Institute, the National Institute on Aging, the National Cancer Institute, and the National Center for Complementary and Integrative Health intend to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Trailblazer Award. This is an opportunity for NIH-defined New and Early Stage Investigators (https://grants.nih.gov/policy/early-investigators/index.htm) to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high-risk high-impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R21 activity code. Investigators with expertise and insights into the application of principles and techniques from engineering and quantitative sciences, such as physics, mathematics, chemistry, and computer sciences are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in trans-disciplinary research approaches with the potential to open new areas of biomedical investigation will be encouraged and these investigators should also begin considering applying for this application.

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 358886
Source ↗ · id

opportunityNumber: FOR-EB-26-001
Source ↗ · opportunityNumber

opportunityTitle: Notice of Intent to Publish a Funding Opportunity Announcement for Trailblazer Award for New and Early-Stage Investigators (R21 Clinical Trial Optional)
Source ↗ · opportunityTitle

revision: 0
Source ↗ · revision

agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode

cfdas: [{"id":428338,"opportunityId":358886,"cfdaNumber":"93.286","programTitle":"Discovery and Applied Research for Technological Innovations to Improve Human Health"}]
Source ↗ · cfdas

forecastDesc: <p><span style="color: rgb(51, 51, 51);">The National Institute of Biomedical Imaging and Bioengineering, with the National Eye Institute, the National Institute on Aging, the National Cancer Institute, and the National Center for Complementary and Integrative Health intend to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Trailblazer Award.&nbsp;This is an opportunity for NIH-defined New and Early Stage Investigators (https://grants.nih.gov/policy/early-investigators/index.htm) to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high-risk high-impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.&nbsp;This NOFO will utilize the R21 activity code. Investigators with expertise and insights into the application of principles and techniques from engineering and quantitative sciences, such as physics, mathematics, chemistry, and computer sciences are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in trans-disciplinary research approaches with the potential to open new areas of biomedical investigation will be encouraged and these investigators should also begin considering applying for this application.&nbsp;</span></p>
Source ↗ · forecastDesc

applicantTypes: [{"id":"00","description":"State governments"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"05","description":"Independent school districts"},{"id":"23","description":"Small businesses"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"20","description":"Private institutions of higher education"},{"id":"01","description":"County governments"},{"id":"22","description":"For profit organizations other than small businesses"}]
Source ↗ · applicantTypes

fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Jun 11, 2025 04:17:58 PM EDT
Source ↗ · lastUpdatedDate

status: forecasted
Source ↗ · oppHits[id=358886].oppStatus

Source retrieved 10/15/2026 · Revision 0. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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