Posted opportunity — confirm at source
Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)
National Institutes of Health · PAR-27-127
See source for award amount
2028-05-25-00-00-00
Confirm exact timezone in the announcement.Private institutions of higher education, City or township governments, County governments, Public and State controlled institutions of higher education, Small businesses, Special district governments, Native American tribal governments (Federally recognized), Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), State governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), For profit organizations other than small businesses, Independent school districts, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Geographic eligibility and all attachment-specific conditions require review of the original announcement.
Eligibility details
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Matching funds & resources
Source matching-funds field: Not Required.
Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.
About this opportunity
This notice of funding opportunity (NOFO) encourages applications for Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. The National Institute of Mental Health (NIMH) seeks teams of integrative researchers working at different levels of analysis and employing novel, and creative experimental approaches to address high-risk, high-impact questions with the primary objectives of: (a) advancing basic brain and behavior research that will uncover underlying mechanisms that could provide the foundation for understanding mental disorders; (b) supporting the integration and translation of basic and clinical neuroscience research on severe mental illnesses; (c) advancing our understanding of the neurobehavioral mechanisms and trajectories of psychopathology that begin in development. This program is intended only for projects that could not be achieved using other, more standard grant mechanisms.
Funding geography: Not specified — review source. A funder’s address does not establish eligibility.
Review original source ↗Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.
Source fields and evidence
id: 360574
Source ↗ · id
opportunityNumber: PAR-27-127
Source ↗ · opportunityNumber
opportunityTitle: Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)
Source ↗ · opportunityTitle
revision: 3
Source ↗ · revision
agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails
owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode
cfdas: [{"id":431081,"opportunityId":360574,"cfdaNumber":"93.242","programTitle":"Mental Health Research Grants"}]
Source ↗ · cfdas
applicantTypes: [{"id":"20","description":"Private institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"01","description":"County governments"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"23","description":"Small businesses"},{"id":"04","description":"Special district governments"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"00","description":"State governments"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"05","description":"Independent school districts"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"}]
Source ↗ · applicantTypes
applicantEligibilityDesc: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Source ↗ · applicantEligibilityDesc
fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments
fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories
awardFloor: none
Source ↗ · awardFloor
awardCeiling: none
Source ↗ · awardCeiling
responseDate: May 25, 2028 12:00:00 AM EDT
Source ↗ · responseDate
responseDateStr: 2028-05-25-00-00-00
Source ↗ · responseDateStr
costSharing: false
Source ↗ · costSharing
lastUpdatedDate: Sep 01, 2026 08:52:56 AM EDT
Source ↗ · lastUpdatedDate
status: posted
Source ↗ · oppHits[id=360574].oppStatus
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