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Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)

National Institutes of Health · PAR-27-078

Award range

Up to $375,000

Deadline

2027-10-25-00-00-00

Confirm exact timezone in the announcement.
Eligible applicants

Private institutions of higher education, Public and State controlled institutions of higher education

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Eligibility details

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

The purpose of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for health professional, undergraduate and graduate students and enhancing the research environment at applicant institutions.Eligible institutions must award baccalaureate or advanced science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F&A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all the schools and colleges within the institution as a whole.Help determining the Organization Funding Level can be found here or https://grants.nih.gov/grants/funding/r15.htmThis REAP Notice of Funding Opportunity (NOFO) supports investigator-initiated mechanistic and/or minimal risk clinical trials addressing the mission and research interests of the participating NIH institutes. For purposes of this NOFO, minimal risk clinical trials are defined as those that do not require FDA oversight, do not intend to formally establish efficacy, and have low risks to potentially cause physical or psychological harm.

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 359733
Source ↗ · id

opportunityNumber: PAR-27-078
Source ↗ · opportunityNumber

opportunityTitle: Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)
Source ↗ · opportunityTitle

revision: 4
Source ↗ · revision

agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode

cfdas: [{"id":433737,"opportunityId":359733,"cfdaNumber":"93.172","programTitle":"Human Genome Research"},{"id":433729,"opportunityId":359733,"cfdaNumber":"93.173","programTitle":"Research Related to Deafness and Communication Disorders"},{"id":433732,"opportunityId":359733,"cfdaNumber":"93.233","programTitle":"National Center on Sleep Disorders Research"},{"id":433740,"opportunityId":359733,"cfdaNumber":"93.242","programTitle":"Mental Health Research Grants"},{"id":433741,"opportunityId":359733,"cfdaNumber":"93.273","programTitle":"Alcohol Research Programs"},{"id":433736,"opportunityId":359733,"cfdaNumber":"93.279","programTitle":"Drug Use and Addiction Research Programs"},{"id":433743,"opportunityId":359733,"cfdaNumber":"93.307","programTitle":"Minority Health and Health Disparities Research"},{"id":433733,"opportunityId":359733,"cfdaNumber":"93.361","programTitle":"Nursing Research"},{"id":433738,"opportunityId":359733,"cfdaNumber":"93.393","programTitle":"Cancer Cause and Prevention Research"},{"id":433734,"opportunityId":359733,"cfdaNumber":"93.394","programTitle":"Cancer Detection and Diagnosis Research"},{"id":433735,"opportunityId":359733,"cfdaNumber":"93.395","programTitle":"Cancer Treatment Research"},{"id":433730,"opportunityId":359733,"cfdaNumber":"93.399","programTitle":"Cancer Control"},{"id":433742,"opportunityId":359733,"cfdaNumber":"93.837","programTitle":"Cardiovascular Diseases Research"},{"id":433744,"opportunityId":359733,"cfdaNumber":"93.838","programTitle":"Lung Diseases Research"},{"id":433731,"opportunityId":359733,"cfdaNumber":"93.839","programTitle":"Blood Diseases and Resources Research"},{"id":433739,"opportunityId":359733,"cfdaNumber":"93.840","programTitle":"Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders"},{"id":433745,"opportunityId":359733,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research"},{"id":429784,"opportunityId":359733,"cfdaNumber":"93.866","programTitle":"Aging Research"},{"id":433746,"opportunityId":359733,"cfdaNumber":"93.867","programTitle":"Vision Research"}]
Source ↗ · cfdas

applicantTypes: [{"id":"20","description":"Private institutions of higher education"},{"id":"06","description":"Public and State controlled institutions of higher education"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

awardFloor: none
Source ↗ · awardFloor

awardCeiling: 375000
Source ↗ · awardCeiling

responseDate: Oct 25, 2027 12:00:00 AM EDT
Source ↗ · responseDate

responseDateStr: 2027-10-25-00-00-00
Source ↗ · responseDateStr

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: May 29, 2026 02:40:59 PM EDT
Source ↗ · lastUpdatedDate

status: posted
Source ↗ · oppHits[id=359733].oppStatus

Related collections: Health funding opportunities · Funding listings for public higher-education institutions · NIH research funding ·

Source retrieved 10/15/2026 · Revision 4. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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