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forecasted

Expanded Surveillance for Pediatric Infectious Diseases

Centers for Disease Control and Prevention - ERA · RFA-IP-27-035

Award range

$850,000 – $1,140,000

Deadline

Not specified

Eligible applicants

State governments, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, City or township governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Independent school districts, Native American tribal organizations (other than Federally recognized tribal governments), County governments, Native American tribal governments (Federally recognized), Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Special district governments, For profit organizations other than small businesses

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

The purpose of this Notice of Funding Opportunity (NOFO) is to support a network of U.S. institutions that will conduct standardized, prospective, active surveillance of pediatric acute respiratory illness (ARI) and acute gastroenteritis (AGE). The network will focus on respiratory and enteric viruses among pediatric patients seeking healthcare. In addition, the network will generate robust estimates of the effectiveness of influenza, rotavirus, respiratory syncytial virus (RSV) and other prevention products against respiratory and enteric viral illnesses in this population. Recipients will identify AGE and ARI illnesses among patients seeking healthcare or diagnostic testing for acute illness among inpatient and emergency department populations. Recipients may also include patients seeking care in outpatient clinics, such as urgent care centers, as an optional activity. This is a multi-component NOFO. You must apply for ComponentA (Core Component). You may also apply for one or more optional components. Component A – Core Component (Required) Support inpatient and emergency department pediatric surveillance Follow the standardized protocol established by CDC Optional Components Component B: Support outpatient pediatric surveillance Component C: Study immune response and infection Component D: Study immune response and immunization Recipients will enroll patients meeting standard symptom criteria and confirm viral infections using approved molecular assays. The network will use the data to estimate prevention product effectiveness, hospitalization rates, and information on the natural history of medically attended diseases. Findings of this NOFO will: Improve best practices for diagnosis and treatment protocols Inform prevention product recommendations Guide public health strategies Reduce viral illness-associated hospitalizations and healthcare utilization among children

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Cooperative Agreement. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 363342
Source ↗ · id

opportunityNumber: RFA-IP-27-035
Source ↗ · opportunityNumber

opportunityTitle: Expanded Surveillance for Pediatric Infectious Diseases
Source ↗ · opportunityTitle

revision: 2
Source ↗ · revision

agencyDetails: {"code":"HHSCDCERA","seed":"HHS-CDC-HHSCDCERA","agencyName":"Centers for Disease Control and Prevention - ERA","agencyCode":"HHS-CDC-HHSCDCERA","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-CDC-HHSCDCERA
Source ↗ · owningAgencyCode

cfdas: [{"id":434741,"opportunityId":363342,"cfdaNumber":"93.083","programTitle":"Prevention of Disease, Disability, and Death through Immunization and Control of Respiratory and Related Diseases"}]
Source ↗ · cfdas

forecastDesc: <p>The purpose of this Notice of Funding Opportunity (NOFO) is to support a network of U.S. institutions that will conduct standardized, prospective, active surveillance of pediatric acute respiratory illness (ARI) and acute gastroenteritis (AGE). The network will focus on respiratory and enteric viruses among pediatric patients seeking healthcare.</p><p>In addition, the network will generate robust estimates of the effectiveness of influenza, rotavirus, respiratory syncytial virus (RSV) and other prevention products against respiratory and enteric viral illnesses in this population.</p><p>Recipients will identify AGE and ARI illnesses among patients seeking healthcare or diagnostic testing for acute illness among inpatient and emergency department populations. Recipients may also include patients seeking care in outpatient clinics, such as urgent care centers, as an optional activity.</p><p>This is a multi-component NOFO. You must apply for ComponentA (Core Component). You may also apply for one or more optional components.</p><p>Component A – Core Component (Required)</p><ul><li data-list-item-id="e02453125fedf0a25d9b7c477f84130c1">Support inpatient and emergency department pediatric surveillance</li><li data-list-item-id="e2f9bf5ad3ad6fbd014a16035f28b2dee">Follow the standardized protocol established by CDC</li></ul><p>Optional Components</p><ul><li data-list-item-id="ef05879876da074312719f95290391a54">Component B: Support outpatient pediatric surveillance</li><li data-list-item-id="e35d0a2fc357242e0d09d2c9462e22566">Component C: Study immune response and infection</li><li data-list-item-id="ed957297655d6c1fcd7bc52f7dc1ad47b">Component D: Study immune response and immunization</li></ul><p>Recipients will enroll patients meeting standard symptom criteria and confirm viral infections using approved molecular assays. The network will use the data to estimate prevention product effectiveness, hospitalization rates, and information on the natural history of medically attended diseases.</p><p>Findings of this NOFO will:</p><ul><li data-list-item-id="ea84fc29ab8071c17c586a6bf9a80cbcc">Improve best practices for diagnosis and treatment protocols</li><li data-list-item-id="e4bba86c08c1ccfe8cf28cf1da2353793">Inform prevention product recommendations</li><li data-list-item-id="e8c0b6d0cb0f7e4fafec792b906f3a024">Guide public health strategies</li><li data-list-item-id="eec92d244743f85c8c220deb2d0abc3bf">Reduce viral illness-associated hospitalizations and healthcare utilization among children</li></ul>
Source ↗ · forecastDesc

applicantTypes: [{"id":"00","description":"State governments"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"02","description":"City or township governments"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"05","description":"Independent school districts"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"01","description":"County governments"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"04","description":"Special district governments"},{"id":"22","description":"For profit organizations other than small businesses"}]
Source ↗ · applicantTypes

fundingInstruments: [{"id":"CA","description":"Cooperative Agreement"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

awardFloor: 850000
Source ↗ · awardFloor

awardCeiling: 1140000
Source ↗ · awardCeiling

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Jul 29, 2026 11:24:52 AM EDT
Source ↗ · lastUpdatedDate

status: forecasted
Source ↗ · oppHits[id=363342].oppStatus

Source retrieved 10/15/2026 · Revision 2. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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