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forecasted

NIOSH Exploratory/Developmental Grant Program (R21)

Centers for Disease Control and Prevention - ERA · RFA-OH-27-033

Award range

$0 – $300,000

Deadline

Not specified

Eligible applicants

County governments, City or township governments, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility", State governments, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Native American tribal governments (Federally recognized), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Public housing authorities/Indian housing authorities, Small businesses, Public and State controlled institutions of higher education, Private institutions of higher education, Native American tribal organizations (other than Federally recognized tribal governments), Independent school districts, Special district governments, For profit organizations other than small businesses

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Eligibility details

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

The R21 grant program is designed to advance our understanding of occupational diseases and injuries by focusing on the following three objectives: Identify the risks and conditions linked to workplace health issues. Develop strategies to reduce risks and limit exposure to hazardous environments. Translate significant scientific discoveries into prevention measures and products that can effectively reduce work-related illnesses and injuries. The National Institute for Occupational Safety and Health (NIOSH) actively supports exploratory and developmental research projects (R21) that pursue: Innovative scientific concepts. New model systems. Tools or technologies with the potential to make a meaningful impact on occupational safety and health. Through this NOFO, applicants will: Provide a clear and concise description of the specific occupational health burden the proposal addresses. Demonstrate how the proposed research activities will lead to outputs that directly contribute to alleviating this burden. Outline the expected outcomes and impacts of their research during the project and in the long term.

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 363327
Source ↗ · id

opportunityNumber: RFA-OH-27-033
Source ↗ · opportunityNumber

opportunityTitle: NIOSH Exploratory/Developmental Grant Program (R21)
Source ↗ · opportunityTitle

revision: 2
Source ↗ · revision

agencyDetails: {"code":"HHSCDCERA","seed":"HHS-CDC-HHSCDCERA","agencyName":"Centers for Disease Control and Prevention - ERA","agencyCode":"HHS-CDC-HHSCDCERA","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-CDC-HHSCDCERA
Source ↗ · owningAgencyCode

cfdas: [{"id":434725,"opportunityId":363327,"cfdaNumber":"93.262","programTitle":"Occupational Safety and Health Program"}]
Source ↗ · cfdas

forecastDesc: <p>The R21 grant program is designed to advance our understanding of occupational diseases and injuries by focusing on the following three objectives:</p><ul><li data-list-item-id="e45380dd694b0da5475422c8b896bfc82">Identify the risks and conditions linked to workplace health issues.</li><li data-list-item-id="ebef7e9a822c9a6169211824849c09892">Develop strategies to reduce risks and limit exposure to hazardous environments.</li><li data-list-item-id="ee1d931d68c20322d6be5cc64c57880d9">Translate significant scientific discoveries into prevention measures and products that can effectively reduce work-related illnesses and injuries.</li></ul><p>The National Institute for Occupational Safety and Health (NIOSH) actively supports exploratory and developmental research projects (R21) that pursue:</p><ul><li data-list-item-id="e173f9488beb787742d0de79ecf504477">Innovative scientific concepts.</li><li data-list-item-id="e55a2491aa9cadbb4af1c6e3dce5729ad">New model systems.</li><li data-list-item-id="e1af3eb7865c82778624088a0ace4bf3a">Tools or technologies with the potential to make a meaningful impact on occupational safety and health.</li></ul><p>Through this NOFO, applicants will:</p><ul><li data-list-item-id="ec244bb52d802b000eb44a00464a5dbf4">Provide a clear and concise description of the specific occupational health burden the proposal addresses. &nbsp;</li><li data-list-item-id="ef37199668a90ae496b10b85d422d0a50">Demonstrate how the proposed research activities will lead to outputs that directly contribute to alleviating this burden.</li><li data-list-item-id="ec86d71af2a9cf4d8bb7945440089709a">Outline the expected outcomes and impacts of their research during the project and in the long term.&nbsp;</li></ul>
Source ↗ · forecastDesc

applicantTypes: [{"id":"01","description":"County governments"},{"id":"02","description":"City or township governments"},{"id":"99","description":"Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled \"Additional Information on Eligibility\""},{"id":"00","description":"State governments"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"23","description":"Small businesses"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"05","description":"Independent school districts"},{"id":"04","description":"Special district governments"},{"id":"22","description":"For profit organizations other than small businesses"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

awardFloor: 0
Source ↗ · awardFloor

awardCeiling: 300000
Source ↗ · awardCeiling

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Jul 29, 2026 11:23:01 AM EDT
Source ↗ · lastUpdatedDate

status: forecasted
Source ↗ · oppHits[id=363327].oppStatus

Source retrieved 10/15/2026 · Revision 2. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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