Posted opportunity — confirm at source
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
National Institutes of Health · PAR-25-378
See source for award amount
2027-01-07-00-00-00
Confirm exact timezone in the announcement.Private institutions of higher education, For profit organizations other than small businesses, Special district governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, Others (see text field entitled "Additional Information on Eligibility" for clarification), County governments, City or township governments, Native American tribal organizations (other than Federally recognized tribal governments), Small businesses, Native American tribal governments (Federally recognized), Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Independent school districts
Geographic eligibility and all attachment-specific conditions require review of the original announcement.
Eligibility details
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Matching funds & resources
Source matching-funds field: Not Required.
Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.
About this opportunity
The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this NOFO, NA includes the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. main land).
Funding geography: Not specified — review source. A funder’s address does not establish eligibility.
Review original source ↗Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.
Source fields and evidence
id: 358373
Source ↗ · id
opportunityNumber: PAR-25-378
Source ↗ · opportunityNumber
opportunityTitle: Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
Source ↗ · opportunityTitle
revision: 2
Source ↗ · revision
agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails
owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode
cfdas: [{"id":427519,"opportunityId":358373,"cfdaNumber":"93.113","programTitle":"Environmental Health"},{"id":427516,"opportunityId":358373,"cfdaNumber":"93.121","programTitle":"Oral Diseases and Disorders Research"},{"id":427523,"opportunityId":358373,"cfdaNumber":"93.213","programTitle":"Research and Training in Complementary and Integrative Health"},{"id":427524,"opportunityId":358373,"cfdaNumber":"93.242","programTitle":"Mental Health Research Grants"},{"id":427517,"opportunityId":358373,"cfdaNumber":"93.273","programTitle":"Alcohol Research Programs"},{"id":427520,"opportunityId":358373,"cfdaNumber":"93.279","programTitle":"Drug Use and Addiction Research Programs"},{"id":427514,"opportunityId":358373,"cfdaNumber":"93.310","programTitle":"Trans-NIH Research Support"},{"id":427521,"opportunityId":358373,"cfdaNumber":"93.313","programTitle":"NIH Office of Research on Women's Health"},{"id":427522,"opportunityId":358373,"cfdaNumber":"93.361","programTitle":"Nursing Research"},{"id":427518,"opportunityId":358373,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research"},{"id":427515,"opportunityId":358373,"cfdaNumber":"93.866","programTitle":"Aging Research"},{"id":427525,"opportunityId":358373}]
Source ↗ · cfdas
applicantTypes: [{"id":"20","description":"Private institutions of higher education"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"04","description":"Special district governments"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"00","description":"State governments"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"01","description":"County governments"},{"id":"02","description":"City or township governments"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"23","description":"Small businesses"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"05","description":"Independent school districts"}]
Source ↗ · applicantTypes
applicantEligibilityDesc: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Source ↗ · applicantEligibilityDesc
fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments
fundingActivityCategories: [{"id":"ED","description":"Education"},{"id":"ENV","description":"Environment"},{"id":"HL","description":"Health"},{"id":"ISS","description":"Income Security and Social Services"}]
Source ↗ · fundingActivityCategories
awardFloor: none
Source ↗ · awardFloor
awardCeiling: none
Source ↗ · awardCeiling
responseDate: Jan 07, 2027 12:00:00 AM EST
Source ↗ · responseDate
responseDateStr: 2027-01-07-00-00-00
Source ↗ · responseDateStr
costSharing: false
Source ↗ · costSharing
lastUpdatedDate: May 22, 2025 01:44:01 PM EDT
Source ↗ · lastUpdatedDate
status: posted
Source ↗ · oppHits[id=358373].oppStatus
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