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forecasted

NIH Director's Early Independence Award (DP5 Clinical Trial Optional)

National Institutes of Health · RFA-RM-28-004

Award range

$350,000 – $350,000

Deadline

Not specified

Eligible applicants

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Small businesses, Public and State controlled institutions of higher education, Private institutions of higher education, State governments, Native American tribal governments (Federally recognized), Special district governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, City or township governments, Independent school districts, Public housing authorities/Indian housing authorities, Others (see text field entitled "Additional Information on Eligibility" for clarification), For profit organizations other than small businesses, County governments, Native American tribal organizations (other than Federally recognized tribal governments)

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Eligibility details

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

The NIH Director's Early Independence Award supports outstanding early-career investigators who are ready to pursue independent research soon after completing their doctoral degree or post-graduate clinical training, without following the traditional postdoctoral path. The award is designed to accelerate the transition to an independent research career. Applications are welcome across all fields relevant to the NIH mission. The Early Independence Award is part of the NIH Common Fund's High-Risk, High-Reward Research Program .

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 363800
Source ↗ · id

opportunityNumber: RFA-RM-28-004
Source ↗ · opportunityNumber

opportunityTitle: NIH Director's Early Independence Award (DP5 Clinical Trial Optional)
Source ↗ · opportunityTitle

revision: 0
Source ↗ · revision

agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode

cfdas: [{"id":435333,"opportunityId":363800,"cfdaNumber":"93.310","programTitle":"Trans-NIH Research Support"}]
Source ↗ · cfdas

forecastDesc: <p>The <a href="https://www.nih.gov/common-fund/common-fund-programs/high-risk-high-reward-research-hrhr/nih-directors-early-independence-award">NIH Director's Early Independence Award</a> supports outstanding early-career investigators who are ready to pursue independent research soon after completing their doctoral degree or post-graduate clinical training, without following the traditional postdoctoral path. The award is designed to accelerate the transition to an independent research career. Applications are welcome across all fields relevant to the NIH mission. The Early Independence Award is part of the NIH Common Fund's <a href="https://www.nih.gov/common-fund/common-fund-programs/high-risk-high-reward-research-hrhr">High-Risk, High-Reward Research Program</a>.</p>
Source ↗ · forecastDesc

applicantTypes: [{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"23","description":"Small businesses"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"20","description":"Private institutions of higher education"},{"id":"00","description":"State governments"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"04","description":"Special district governments"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"05","description":"Independent school districts"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"01","description":"County governments"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

awardFloor: 350000
Source ↗ · awardFloor

awardCeiling: 350000
Source ↗ · awardCeiling

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Sep 03, 2026 02:13:59 PM EDT
Source ↗ · lastUpdatedDate

status: forecasted
Source ↗ · oppHits[id=363800].oppStatus

Source retrieved 10/15/2026 · Revision 0. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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