Posted opportunity — confirm at source
GREGoRi Innovation Projects (U01 Clinical Trial Optional)
National Institutes of Health · RFA-HG-27-013
$3 – $500,000
2026-10-30-00-00-00
Confirm exact timezone in the announcement.City or township governments, Independent school districts, Native American tribal governments (Federally recognized), Public and State controlled institutions of higher education, County governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), Private institutions of higher education, Public housing authorities/Indian housing authorities, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses, Native American tribal organizations (other than Federally recognized tribal governments), State governments, Special district governments, Small businesses, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Geographic eligibility and all attachment-specific conditions require review of the original announcement.
Eligibility details
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Matching funds & resources
Source matching-funds field: Not Required.
Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.
About this opportunity
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Funding geography: Not specified — review source. A funder’s address does not establish eligibility.
Review original source ↗Funding instrument: Cooperative Agreement. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.
Source fields and evidence
id: 359644
Source ↗ · id
opportunityNumber: RFA-HG-27-013
Source ↗ · opportunityNumber
opportunityTitle: GREGoRi Innovation Projects (U01 Clinical Trial Optional)
Source ↗ · opportunityTitle
revision: 3
Source ↗ · revision
agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails
owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode
cfdas: [{"id":429507,"opportunityId":359644,"cfdaNumber":"93.172","programTitle":"Human Genome Research"}]
Source ↗ · cfdas
applicantTypes: [{"id":"02","description":"City or township governments"},{"id":"05","description":"Independent school districts"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"01","description":"County governments"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"20","description":"Private institutions of higher education"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"00","description":"State governments"},{"id":"04","description":"Special district governments"},{"id":"23","description":"Small businesses"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"}]
Source ↗ · applicantTypes
applicantEligibilityDesc: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Source ↗ · applicantEligibilityDesc
fundingInstruments: [{"id":"CA","description":"Cooperative Agreement"}]
Source ↗ · fundingInstruments
fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories
awardFloor: 3
Source ↗ · awardFloor
awardCeiling: 500000
Source ↗ · awardCeiling
responseDate: Oct 30, 2026 12:00:00 AM EDT
Source ↗ · responseDate
responseDateStr: 2026-10-30-00-00-00
Source ↗ · responseDateStr
costSharing: false
Source ↗ · costSharing
lastUpdatedDate: Jun 18, 2026 02:11:37 PM EDT
Source ↗ · lastUpdatedDate
status: posted
Source ↗ · oppHits[id=359644].oppStatus
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