Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)

id: 362978
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opportunityNumber: RFA-ES-28-002
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opportunityTitle: Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)
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revision: 0
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agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
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owningAgencyCode: HHS-NIH11
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cfdas: [{"id":434322,"opportunityId":362978,"cfdaNumber":"93.113","programTitle":"Environmental Health"}]
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forecastDesc: <p>The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose translational research hubs with multiple highly integrated components focused on research, capacity building, and community/public health translation for regionally relevant topics related to the health impacts of extreme weather and cumulative exposures,&nbsp;including but not limited to wildfire smoke, extreme heat, flooding, hurricanes, drought, and other climate-related hazards affecting populations at heightened risk across the lifespan. Responsive applications will be led by a multidisciplinary team of investigators with non-academic partners,&nbsp;such as state and local public health departments, community-based organizations, Tribal entities, health care systems, and emergency preparedness agencies. &nbsp;Consortia of multiple institutions are encouraged,&nbsp;particularly those that demonstrate meaningful community engagement and balanced, mutually beneficial partnership structures. Research can be situated at different nodes on the translational research continuum,<strong>&nbsp;</strong>spanning from fundamental to implementation research with a focus on being problem-based and solutions oriented,&nbsp;and should clearly inform pathways to support implementation, scalability, and measurable public health impact.&nbsp;Award recipients will be expected to collaborate with the HEW Research Coordination and Data Center(s) and other members of the HEW Community of Practice,&nbsp;including participation in data harmonization efforts, shared metrics development, and cross-site dissemination activities.&nbsp;<span style="background-color:white;">This NOFO will&nbsp;utilize&nbsp;the U54 activity code, that&nbsp;supports specialized centers that function as regional resources for targeted research initiatives, including support for infrastructure development, pilot projects, and partnerships with affected communities throughout the research lifecycle. The U54 is a cooperative agreement&nbsp;that anticipates&nbsp;substantial federal programmatic staff involvement to&nbsp;assist&nbsp;investigators in the achievement of project objectives</span>,&nbsp;including coordination across funded hubs, strategic alignment with NIH priorities, and facilitation of cross-institute collaboration<span style="background-color:white;">.&nbsp;</span>Grant authorities that allow NIEHS to forecast this opportunity are as follows: 42 USC 285l (NIEHS specific); 42 USC sections 241 (NIH grant authorities).</p>
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applicantTypes: [{"id":"20","description":"Private institutions of higher education"},{"id":"02","description":"City or township governments"},{"id":"01","description":"County governments"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"05","description":"Independent school districts"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"00","description":"State governments"},{"id":"04","description":"Special district governments"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"23","description":"Small businesses"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"}]
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applicantEligibilityDesc: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations
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fundingInstruments: [{"id":"CA","description":"Cooperative Agreement"}]
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fundingActivityCategories: [{"id":"HL","description":"Health"}]
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awardCeiling: 2000000
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costSharing: false
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lastUpdatedDate: Jun 26, 2026 09:00:54 AM EDT
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status: forecasted
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