forecasted
Elucidation and Validation of the role of Transporters in the Placenta, Lactating Mammary Gland, Developing Gut, and Blood Brain Barrier
National Institutes of Health · RFA-HD-28-003
See source for award amount
Not specified
Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), County governments, Small businesses, City or township governments, Independent school districts, Special district governments, Private institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification), For profit organizations other than small businesses, Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, Public housing authorities/Indian housing authorities, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Geographic eligibility and all attachment-specific conditions require review of the original announcement.
Eligibility details
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Matching funds & resources
Source matching-funds field: Not Required.
Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.
About this opportunity
The Eunice Kennedy Shriver National Institute of Child Health and Human Development seeks to advance its mission of supporting maternal, fetal, and child health by continuing to enhance the understanding of maternal, fetal, and child exposure to nutrients, metabolites, medications, supplements, microbiome-derived products, and environmental chemicals. This will be done by supporting a second phase of the Transporter Elucidation Network (TEN). This phase of the TEN will establish perinatal multi-barrier transport network frameworks to clarify how transporters and local biotransformation regulate these processes. Building on prior organ-focused models, methods, and datasets, this initiative will develop standards, resources, models, and prototype multi-compartment approaches spanning maternal gut, placenta, lactating mammary epithelium, infant gut, and infant blood-brain barrier. The initiative is expected to support a mechanistic understanding of transporter function, polarity, kinetics, and transformation capacity relevant to pregnancy, lactation, infant nutrition, pediatric pharmacology, and neurodevelopment. By emphasizing multi-barrier perinatal transporter frameworks this phase of the TEN will provide community resources for future integrated studies of perinatal exposure, risk, and intervention across interlinked maternal, fetal, and infant systems. It will also strengthen coordination among investigators, accelerate dissemination of tools, and advance human-based, developmentally relevant transporter research and workforce development. The grant authority for this is 42 U.S.C. § 241
Funding geography: Not specified — review source. A funder’s address does not establish eligibility.
Review original source ↗Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.
Source fields and evidence
id: 363210
Source ↗ · id
opportunityNumber: RFA-HD-28-003
Source ↗ · opportunityNumber
opportunityTitle: Elucidation and Validation of the role of Transporters in the Placenta, Lactating Mammary Gland, Developing Gut, and Blood Brain Barrier
Source ↗ · opportunityTitle
revision: 0
Source ↗ · revision
agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails
owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode
cfdas: [{"id":434590,"opportunityId":363210,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research"}]
Source ↗ · cfdas
forecastDesc: <p>The <i>Eunice Kennedy Shriver </i>National Institute of Child Health and Human Development seeks to advance its mission of supporting maternal, fetal, and child health by continuing to enhance the understanding of maternal, fetal, and child exposure to nutrients, metabolites, medications, supplements, microbiome-derived products, and environmental chemicals. This will be done by supporting a second phase of the Transporter Elucidation Network (TEN). This phase of the TEN will establish perinatal multi-barrier transport network frameworks to clarify how transporters and local biotransformation regulate these processes. Building on prior organ-focused models, methods, and datasets, this initiative will develop standards, resources, models, and prototype multi-compartment approaches spanning maternal gut, placenta, lactating mammary epithelium, infant gut, and infant blood-brain barrier. The initiative is expected to support a mechanistic understanding of transporter function, polarity, kinetics, and transformation capacity relevant to pregnancy, lactation, infant nutrition, pediatric pharmacology, and neurodevelopment. By emphasizing multi-barrier perinatal transporter frameworks this phase of the TEN will provide community resources for future integrated studies of perinatal exposure, risk, and intervention across interlinked maternal, fetal, and infant systems. It will also strengthen coordination among investigators, accelerate dissemination of tools, and advance human-based, developmentally relevant transporter research and workforce development. The grant authority for this is 42 U.S.C. § 241 </p>
Source ↗ · forecastDesc
applicantTypes: [{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"01","description":"County governments"},{"id":"23","description":"Small businesses"},{"id":"02","description":"City or township governments"},{"id":"05","description":"Independent school districts"},{"id":"04","description":"Special district governments"},{"id":"20","description":"Private institutions of higher education"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"00","description":"State governments"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"}]
Source ↗ · applicantTypes
applicantEligibilityDesc: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Source ↗ · applicantEligibilityDesc
fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments
fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories
costSharing: false
Source ↗ · costSharing
lastUpdatedDate: Jul 16, 2026 10:58:45 AM EDT
Source ↗ · lastUpdatedDate
status: forecasted
Source ↗ · oppHits[id=363210].oppStatus
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