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Posted opportunity — confirm at source

Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)

National Institutes of Health · PAR-27-072

Award range

Up to $500,000

Deadline

2029-07-05-00-00-00

Confirm exact timezone in the announcement.
Eligible applicants

Native American tribal organizations (other than Federally recognized tribal governments), Private institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification), Small businesses, Independent school districts, Native American tribal governments (Federally recognized), Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, City or township governments, For profit organizations other than small businesses, Public housing authorities/Indian housing authorities, Special district governments, County governments

Geographic eligibility and all attachment-specific conditions require review of the original announcement.

Eligibility details

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Matching funds & resources

Source matching-funds field: Not Required.

Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.

About this opportunity

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support conventional clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials in any area of research are not sought by and will not be supported through this NOFO. This NOFO does not support commercial production.

Funding geography: Not specified — review source. A funder’s address does not establish eligibility.

Review original source ↗

Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.

Source fields and evidence

id: 360543
Source ↗ · id

opportunityNumber: PAR-27-072
Source ↗ · opportunityNumber

opportunityTitle: Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)
Source ↗ · opportunityTitle

revision: 5
Source ↗ · revision

agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails

owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode

cfdas: [{"id":431043,"opportunityId":360543,"cfdaNumber":"93.393","programTitle":"Cancer Cause and Prevention Research"},{"id":431042,"opportunityId":360543,"cfdaNumber":"93.394","programTitle":"Cancer Detection and Diagnosis Research"},{"id":431041,"opportunityId":360543,"cfdaNumber":"93.395","programTitle":"Cancer Treatment Research"},{"id":431044,"opportunityId":360543,"cfdaNumber":"93.396","programTitle":"Cancer Biology Research"},{"id":431045,"opportunityId":360543,"cfdaNumber":"93.399","programTitle":"Cancer Control"},{"id":435234,"opportunityId":360543,"cfdaNumber":"93.853","programTitle":"Extramural Research Programs in the Neurosciences and Neurological Disorders"},{"id":433053,"opportunityId":360543,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research"},{"id":433054,"opportunityId":360543,"cfdaNumber":"93.867","programTitle":"Vision Research"},{"id":433055,"opportunityId":360543}]
Source ↗ · cfdas

applicantTypes: [{"id":"11","description":"Native American tribal organizations (other than Federally recognized tribal governments)"},{"id":"20","description":"Private institutions of higher education"},{"id":"13","description":"Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"25","description":"Others (see text field entitled \"Additional Information on Eligibility\" for clarification)"},{"id":"23","description":"Small businesses"},{"id":"05","description":"Independent school districts"},{"id":"07","description":"Native American tribal governments (Federally recognized)"},{"id":"06","description":"Public and State controlled institutions of higher education"},{"id":"12","description":"Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education"},{"id":"00","description":"State governments"},{"id":"02","description":"City or township governments"},{"id":"22","description":"For profit organizations other than small businesses"},{"id":"08","description":"Public housing authorities/Indian housing authorities"},{"id":"04","description":"Special district governments"},{"id":"01","description":"County governments"}]
Source ↗ · applicantTypes

applicantEligibilityDesc: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Source ↗ · applicantEligibilityDesc

fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments

fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories

awardFloor: none
Source ↗ · awardFloor

awardCeiling: 500000
Source ↗ · awardCeiling

responseDate: Jul 05, 2029 12:00:00 AM EDT
Source ↗ · responseDate

responseDateStr: 2029-07-05-00-00-00
Source ↗ · responseDateStr

costSharing: false
Source ↗ · costSharing

lastUpdatedDate: Aug 28, 2026 11:29:03 AM EDT
Source ↗ · lastUpdatedDate

status: posted
Source ↗ · oppHits[id=360543].oppStatus

Source retrieved 10/15/2026 · Revision 5. Always confirm current requirements and dates with the funder. Structured source fields are checked; this is not a determination that every applicant qualifies.

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