forecasted
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
National Institutes of Health · PAR-27-040
See source for award amount
Not specified
Small businesses
Geographic eligibility and all attachment-specific conditions require review of the original announcement.
Eligibility details
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.
Matching funds & resources
Source matching-funds field: Not Required.
Matching funds and leveraged resources are different requirements. Read the description and reviewed rules below before determining resource commitments.
About this opportunity
The National Institutes of Health (NIH), including the participating Institutes, Centers and Offices, intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) Phase I, and Fast-Track grant applications for the Small Business Transition Grant. Through this NOFO, NIH will support early-career scientists transitioning to entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R41/R42 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project.
Funding geography: Not specified — review source. A funder’s address does not establish eligibility.
Review original source ↗Funding instrument: Grant. Issuing jurisdiction: Federal. This is not a geographic eligibility determination.
Source fields and evidence
id: 362577
Source ↗ · id
opportunityNumber: PAR-27-040
Source ↗ · opportunityNumber
opportunityTitle: Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
Source ↗ · opportunityTitle
revision: 0
Source ↗ · revision
agencyDetails: {"code":"NIH","seed":"HHS-NIH11","agencyName":"National Institutes of Health","agencyCode":"HHS-NIH11","topAgencyCode":"HHS"}
Source ↗ · agencyDetails
owningAgencyCode: HHS-NIH11
Source ↗ · owningAgencyCode
cfdas: [{"id":433651,"opportunityId":362577,"cfdaNumber":"93.113","programTitle":"Environmental Health"},{"id":433655,"opportunityId":362577,"cfdaNumber":"93.121","programTitle":"Oral Diseases and Disorders Research"},{"id":433646,"opportunityId":362577,"cfdaNumber":"93.172","programTitle":"Human Genome Research"},{"id":433642,"opportunityId":362577,"cfdaNumber":"93.173","programTitle":"Research Related to Deafness and Communication Disorders"},{"id":433643,"opportunityId":362577,"cfdaNumber":"93.213","programTitle":"Research and Training in Complementary and Integrative Health"},{"id":433647,"opportunityId":362577,"cfdaNumber":"93.233","programTitle":"National Center on Sleep Disorders Research"},{"id":433656,"opportunityId":362577,"cfdaNumber":"93.273","programTitle":"Alcohol Research Programs"},{"id":433645,"opportunityId":362577,"cfdaNumber":"93.279","programTitle":"Drug Use and Addiction Research Programs"},{"id":433652,"opportunityId":362577,"cfdaNumber":"93.350","programTitle":"National Center for Advancing Translational Sciences"},{"id":433641,"opportunityId":362577,"cfdaNumber":"93.361","programTitle":"Nursing Research"},{"id":433653,"opportunityId":362577,"cfdaNumber":"93.837","programTitle":"Cardiovascular Diseases Research"},{"id":433648,"opportunityId":362577,"cfdaNumber":"93.838","programTitle":"Lung Diseases Research"},{"id":433650,"opportunityId":362577,"cfdaNumber":"93.839","programTitle":"Blood Diseases and Resources Research"},{"id":433640,"opportunityId":362577,"cfdaNumber":"93.840","programTitle":"Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders"},{"id":433657,"opportunityId":362577,"cfdaNumber":"93.846","programTitle":"Arthritis, Musculoskeletal and Skin Diseases Research"},{"id":433639,"opportunityId":362577,"cfdaNumber":"93.859","programTitle":"Biomedical Research and Research Training"},{"id":433649,"opportunityId":362577,"cfdaNumber":"93.865","programTitle":"Child Health and Human Development Extramural Research"},{"id":433644,"opportunityId":362577,"cfdaNumber":"93.866","programTitle":"Aging Research"},{"id":433654,"opportunityId":362577,"cfdaNumber":"93.867","programTitle":"Vision Research"},{"id":433658,"opportunityId":362577,"cfdaNumber":"93.879","programTitle":"Medical Library Assistance"}]
Source ↗ · cfdas
forecastDesc: <p>The National Institutes of Health (NIH), including the participating Institutes, Centers and Offices, intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) Phase I, and Fast-Track grant applications for the Small Business Transition Grant. Through this NOFO, NIH will support early-career scientists transitioning to entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI.</p><p>Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R41/R42 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project. </p>
Source ↗ · forecastDesc
applicantTypes: [{"id":"23","description":"Small businesses"}]
Source ↗ · applicantTypes
applicantEligibilityDesc: Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.
Source ↗ · applicantEligibilityDesc
fundingInstruments: [{"id":"G","description":"Grant"}]
Source ↗ · fundingInstruments
fundingActivityCategories: [{"id":"HL","description":"Health"}]
Source ↗ · fundingActivityCategories
costSharing: false
Source ↗ · costSharing
lastUpdatedDate: May 27, 2026 02:05:27 PM EDT
Source ↗ · lastUpdatedDate
status: forecasted
Source ↗ · oppHits[id=362577].oppStatus
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